Structural Dynamics of Soluble Chloride Intracellular Channel Protein CLIC1 Examined by Amide Hydrogen-Deuterium Exchange Mass Spectrometry (DXMS)

Chloride intracellular channel protein 1 (CLIC1) functions as an anion channel in plasma and nuclear membranes when its soluble monomeric form converts to an integral-membrane form. The transmembrane region of CLIC1 is located in its thioredoxin-like domain 1 but the mechanism whereby the protein co...

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Detalhes bibliográficos
Main Authors: Stoychev, Stoyan H., Nathaniel, Christos, Fanucchi, Sylvia, Brock, Melissa, Li, Sheng, Asmus, Kyle, Woods, Virgil L., Dirr, Heini W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752679/
https://ncbi.nlm.nih.gov/pubmed/19650640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9010607
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