Construct Optimization for Protein NMR Structure Analysis Using Amide Hydrogen / Deuterium Exchange Mass Spectrometry

Disordered or unstructured regions of proteins, while often very important biologically, can pose significant challenges for resonance assignment and three-dimensional structure determination of the ordered regions of proteins by NMR methods. In this paper, we demonstrate the application of (1)H/(2)...

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Detalhes bibliográficos
Main Authors: Sharma, Seema, Zheng, Haiyan, Huang, Yuanpeng J., Ertekin, Asli, Hamuro, Yoshitomo, Rossi, Paolo, Tejero, Roberto, Acton, Thomas B., Xiao, Rong, Jiang, Mei, Zhao, Li, Ma, Li-Chung, Swapna, G. V. T., Aramini, James M., Montelione, Gaetano T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739808/
https://ncbi.nlm.nih.gov/pubmed/19306341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22394
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