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Hydrogen/deuterium-exchange (H/D-Ex) of PPARγ LBD in the presence of various modulators

A nuclear receptor, peroxisome proliferator-activated receptor γ (PPARγ), is a ligand-dependent transcription factor involved in glucose homeostasis and adipocyte differentiation. PPARγ is the molecular target of various natural and synthetic molecules, including anti-diabetic agents such as rosigli...

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Detalhes bibliográficos
Main Authors: Hamuro, Yoshitomo, Coales, Stephen J., Morrow, Jeffrey A., Molnar, Kathleen S., Tuske, Steven J., Southern, Mark R., Griffin, Patrick R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242592/
https://ncbi.nlm.nih.gov/pubmed/16823031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062103006
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