CA125 effects on humoral immunosuppression

por Kline, J. Bradford, Nicolaides, Nicholas C.
Publicado en Aging (Albany NY) (2017)

Co-Development of Diagnostic Vectors to Support Targeted Therapies and Theranostics: Essential Tools in Personalized Cancer Therapy

por Nicolaides, Nicholas C., O’Shannessy, Daniel J., Albone, Earl, Grasso, Luigi
Publicado 2014

A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype

por Nicolaides, Nicholas C., Littman, Susan J., Modrich, Paul, Kinzler, Kenneth W., Vogelstein, Bert
Publicado 1998

Influence of tumor microenvironment on prognosis in colorectal cancer: Tissue architecture-dependent signature of endosialin (TEM-1) and associated proteins

por O'Shannessy, Daniel J., Somers, Elizabeth B., Chandrasekaran, Lakshmi K., Nicolaides, Nicholas C., Bordeaux, Jennifer, Gustavson, Mark D.
Publicado 2014

Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration

por Tomkowicz, Brian, Rybinski, Katherine, Foley, Brian, Ebel, Wolfgang, Kline, Brad, Routhier, Eric, Sass, Philip, Nicolaides, Nicholas C., Grasso, Luigi, Zhou, Yuhong
Publicado 2007

CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients

por Nicolaides, Nicholas C., Schweizer, Charles, Somers, Elizabeth B., Wang, Wenquan, Fernando, Shawn, Ross, Erin N., Grasso, Luigi, Hassan, Raffit, Kline, J. Bradford
Publicado en Cancer Biol Ther (2018)

Development of (124)I-Immuno-PET Targeting Tumor Vascular TEM1/Endosialin

por Chacko, Ann-Marie, Li, Chunsheng, Nayak, Madhura, Mikitsh, John L., Hu, Jia, Hou, Catherine, Grasso, Luigi, Nicolaides, Nicholas C., Muzykantov, Vladimir R., Divgi, Chaitanya R., Coukos, George
Publicado 2014

Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement

por Kline, James Bradford, Kennedy, Rina P., Albone, Earl, Chao, Qimin, Fernando, Shawn, McDonough, Jennifer M., Rybinski, Katherine, Wang, Wenquan, Somers, Elizabeth B., Schweizer, Charles, Grasso, Luigi, Nicolaides, Nicholas C.
Publicado en Oncotarget (2017)

Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B

por Drozdowski, Brian, Zhou, Yuhong, Kline, Brad, Spidel, Jared, Chan, Yin Yin, Albone, Earl, Turchin, Howard, Chao, Qimin, Henry, Marianne, Balogach, Jacqueline, Routhier, Eric, Bavari, Sina, Nicolaides, Nicholas C, Sass, Philip M, Grasso, Luigi
Publicado 2010

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes

por O'Shannessy, Daniel J., Somers, Elizabeth B., Albone, Earl, Cheng, Xin, Park, Young Chul, Tomkowicz, Brian E., Hamuro, Yoshitomo, Kohl, Thomas O., Forsyth, Tracy M., Smale, Robert, Fu, Yao-Shi, Nicolaides, Nicholas C.
Publicado 2011

Novel antibody probes for the characterization of endosialin/TEM-1

por O'shannessy, Daniel J., Smith, Michael F., Somers, Elizabeth B., Jackson, Stephen M., Albone, Earl, Tomkowicz, Brian, Cheng, Xin, Park, Young, Fernando, Danielle, Milinichik, Andrew, Kline, Brad, Fulton, Regan, Oberoi, Pankaj, Nicolaides, Nicholas C.
Publicado en Oncotarget (2016)

Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature

por Rybinski, Katherine, Imtiyaz, Hongxia Z., Mittica, Barrie, Drozdowski, Brian, Fulmer, James, Furuuchi, Keiji, Fernando, Shawn, Henry, Marianne, Chao, Qimin, Kline, Brad, Albone, Earl, Wustner, Jason, Lin, JianMin, Nicolaides, Nicholas C., Grasso, Luigi, Zhou, Yuhong
Publicado en Oncotarget (2015)

Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures

por Finnberg, Niklas K., Gokare, Prashanth, Lev, Avital, Grivennikov, Sergei I., MacFarlane, Alexander W., Campbell, Kerry S., Winters, Ryan M., Kaputa, Karen, Farma, Jeffrey M., Abbas, Abbas El-Sayed, Grasso, Luigi, Nicolaides, Nicholas C., El-Deiry, Wafik S.
Publicado en Oncotarget (2017)

Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha

por Ebel, Wolfgang, Routhier, Eric L., Foley, Brian, Jacob, Sara, McDonough, Jennifer M., Patel, Rina K., Turchin, Howard A., Chao, Qimin, Kline, J. Bradford, Old, Lloyd J., Phillips, Martin D., Nicolaides, Nicholas C., Sass, Philip M., Grasso, Luigi
Publicado 2007

Interleukin 9: A candidate gene for asthma

por Nicolaides, Nicholas C., Holroyd, Kenneth J., Ewart, Susan L., Eleff, Scott M., Kiser, Matthew B., Dragwa, Carl R., Sullivan, Christine D., Grasso, Luigi, Zhang, Liu-Yi, Messler, Carol J., Zhou, Tingyi, Kleeberger, Steven R., Buetow, Kenneth H., Levitt, Roy C.
Publicado 1997

The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity

por Lin, JianMin, Spidel, Jared L, Maddage, Christopher J, Rybinski, Katherine A, Kennedy, Rina P, Krauthauser, Candice LM, Park, Young Chul, Albone, Earl F, Jacob, Sara, Goserud, Matthew T, Martinez, Bryon P, Chao, Qimin, Zhou, Yuhong, Nicolaides, Nicholas C, Kline, J Bradford, Grasso, Luigi
Publicado 2013

Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin

por Hassan, Raffit, Ebel, Wolfgang, Routhier, Eric L., Patel, Rina, Kline, J. Bradford, Zhang, Jingli, Chao, Qimin, Jacob, Sara, Turchin, Howard, Gibbs, Lester, Phillips, Martin D., Mudali, Shiyama, Iacobuzio-Donahue, Christine, Jaffee, Elizabeth M., Moreno, Maria, Pastan, Ira, Sass, Philip M., Nicolaides, Nicholas C., Grasso, Luigi
Publicado 2007

Human antibodies for immunotherapy development generated via a human B cell hybridoma technology

por Li, Jian, Sai, Tao, Berger, Marc, Chao, Qimin, Davidson, Diane, Deshmukh, Gaurav, Drozdowski, Brian, Ebel, Wolfgang, Harley, Stephen, Henry, Marianne, Jacob, Sara, Kline, Brad, Lazo, Ella, Rotella, Frank, Routhier, Eric, Rudolph, Kathryn, Sage, Jeaneen, Simon, Paul, Yao, Jun, Zhou, Yuhong, Kavuru, Mani, Bonfield, Tracey, Thomassen, Mary Jane, Sass, Philip M., Nicolaides, Nicholas C., Grasso, Luigi
Publicado 2006