Human antibodies for immunotherapy development generated via a human B cell hybridoma technology

Current strategies for the production of therapeutic mAbs include the use of mammalian cell systems to recombinantly produce Abs derived from mice bearing human Ig transgenes, humanization of rodent Abs, or phage libraries. Generation of hybridomas secreting human mAbs has been previously reported;...

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Detalles Bibliográficos
Main Authors: Li, Jian, Sai, Tao, Berger, Marc, Chao, Qimin, Davidson, Diane, Deshmukh, Gaurav, Drozdowski, Brian, Ebel, Wolfgang, Harley, Stephen, Henry, Marianne, Jacob, Sara, Kline, Brad, Lazo, Ella, Rotella, Frank, Routhier, Eric, Rudolph, Kathryn, Sage, Jeaneen, Simon, Paul, Yao, Jun, Zhou, Yuhong, Kavuru, Mani, Bonfield, Tracey, Thomassen, Mary Jane, Sass, Philip M., Nicolaides, Nicholas C., Grasso, Luigi
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383494/
https://ncbi.nlm.nih.gov/pubmed/16505368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511285103
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