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Human antibodies for immunotherapy development generated via a human B cell hybridoma technology
Current strategies for the production of therapeutic mAbs include the use of mammalian cell systems to recombinantly produce Abs derived from mice bearing human Ig transgenes, humanization of rodent Abs, or phage libraries. Generation of hybridomas secreting human mAbs has been previously reported;...
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383494/ https://ncbi.nlm.nih.gov/pubmed/16505368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511285103 |
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