Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha

The highly restricted distribution of human folate receptor-alpha (FRα) in normal tissues and its high expression in some tumors, along with its putative role in tumor cell transformation, make this antigen a suitable target for antigen-specific, monoclonal antibody-based immunotherapy for oncology...

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Detalhes bibliográficos
Main Authors: Ebel, Wolfgang, Routhier, Eric L., Foley, Brian, Jacob, Sara, McDonough, Jennifer M., Patel, Rina K., Turchin, Howard A., Chao, Qimin, Kline, J. Bradford, Old, Lloyd J., Phillips, Martin D., Nicolaides, Nicholas C., Sass, Philip M., Grasso, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Academy of Cancer Immunology 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935753/
https://ncbi.nlm.nih.gov/pubmed/17346028
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