Preclinical Radioimmunotargeting of Folate Receptor Alpha using the Monoclonal Antibody Conjugate DOTA-MORAb-003

INTRODUCTION: The in vitro and in vivo behavior of the radiolabeled monoclonal antibody MORAb-003 was investigated as a prelude to a clinical trial. METHODS: The cellular rentention of (111)In and (131)I labeled MORAb-003 were investigated using IGROV1 and SW620 cells. Biodistribution studies in tum...

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Main Authors: Smith-Jones, P. M., Taskar, N. Pandit, Cao, W., O'Donoghue, J., Philips, M.D., Carrasquillo, J., Konner, J, Old, L.J., Larson, S.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676680/
https://ncbi.nlm.nih.gov/pubmed/18355690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.12.008
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