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Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha
The highly restricted distribution of human folate receptor-alpha (FRα) in normal tissues and its high expression in some tumors, along with its putative role in tumor cell transformation, make this antigen a suitable target for antigen-specific, monoclonal antibody-based immunotherapy for oncology...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Academy of Cancer
Immunology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935753/ https://ncbi.nlm.nih.gov/pubmed/17346028 |
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