The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity

Because of its high mortality rate, ovarian cancer is a leading cause of death among women and a highly unmet medical need. New therapeutic agents that are effective and well tolerated are needed and cancer antigen-specific monoclonal antibodies that have direct pharmacologic effects or can stimulat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lin, JianMin, Spidel, Jared L, Maddage, Christopher J, Rybinski, Katherine A, Kennedy, Rina P, Krauthauser, Candice LM, Park, Young Chul, Albone, Earl F, Jacob, Sara, Goserud, Matthew T, Martinez, Bryon P, Chao, Qimin, Zhou, Yuhong, Nicolaides, Nicholas C, Kline, J Bradford, Grasso, Luigi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2013
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925658/
https://ncbi.nlm.nih.gov/pubmed/24025360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.26106
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