Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice

Resveratrol, a polyphenolic-stilbene, has received increased attention in the last decade due to its wide range of biological activities. Beta(β)-thalassemias are inherited red cell disorders, found worldwide, characterized by ineffective erythropoiesis and red cell oxidative damage with reduced sur...

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Main Authors: Franco, Sara Santos, De Falco, Luigia, Ghaffari, Saghi, Brugnara, Carlo, Sinclair, David A., Matte’, Alessandro, Iolascon, Achille, Mohandas, Narla, Bertoldi, Mariarita, An, Xiuli, Siciliano, Angela, Rimmelé, Pauline, Cappellini, Maria Domenica, Michan, Shaday, Zoratti, Elisa, Anne, Janin, De Franceschi, Lucia
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912956/
https://ncbi.nlm.nih.gov/pubmed/23975182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.090076
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