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Peroxiredoxin-2 expression is increased in β-thalassemic mouse red cells but is displaced from the membrane as a marker of oxidative stress

Peroxiredoxin 2 (Prx2), the third most abundant cytoplasmic protein in red blood cells (RBCs), is involved in the defense against oxidative stress. Although much is known about Prx2 in healthy RBCs, its role in pathological RBCs remains largely unexplored. Here, we show that the expression and net c...

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Detalhes bibliográficos
Main Authors: Matte, Alessandro, Low, Philip S., Turrini, Franco, Bertoldi, Mariarita, Campanella, Maria Estela, Spano, Daniela, Pantaleo, Antonella, Siciliano, Angela, De Franceschi, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395234/
https://ncbi.nlm.nih.gov/pubmed/20488244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.05.003
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