Peroxiredoxin-2 expression is increased in β-thalassemic mouse red cells but is displaced from the membrane as a marker of oxidative stress

Peroxiredoxin 2 (Prx2), the third most abundant cytoplasmic protein in red blood cells (RBCs), is involved in the defense against oxidative stress. Although much is known about Prx2 in healthy RBCs, its role in pathological RBCs remains largely unexplored. Here, we show that the expression and net c...

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Hlavní autoři: Matte, Alessandro, Low, Philip S., Turrini, Franco, Bertoldi, Mariarita, Campanella, Maria Estela, Spano, Daniela, Pantaleo, Antonella, Siciliano, Angela, De Franceschi, Lucia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395234/
https://ncbi.nlm.nih.gov/pubmed/20488244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.05.003
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