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Peroxiredoxin-2 expression is increased in β-thalassemic mouse red cells but is displaced from the membrane as a marker of oxidative stress

Peroxiredoxin 2 (Prx2), the third most abundant cytoplasmic protein in red blood cells (RBCs), is involved in the defense against oxidative stress. Although much is known about Prx2 in healthy RBCs, its role in pathological RBCs remains largely unexplored. Here, we show that the expression and net c...

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Opis bibliograficzny
Główni autorzy: Matte, Alessandro, Low, Philip S., Turrini, Franco, Bertoldi, Mariarita, Campanella, Maria Estela, Spano, Daniela, Pantaleo, Antonella, Siciliano, Angela, De Franceschi, Lucia
Format: Artigo
Język:Inglês
Wydane: 2010
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395234/
https://ncbi.nlm.nih.gov/pubmed/20488244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.05.003
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