Protocol for a pilot randomised controlled trial of metformin in pre-diabetes after kidney transplantation: the Transplantation and Diabetes (Transdiab) study

Por Alnasrallah, Basil, Pilmore, Helen, Manley, Paul
Publicado no BMJ Open (2017)

A DEMONSTRATION OF SEVERAL DEOXYRIBONUCLEASE ACTIVITIES IN MAMMALIAN CELL MITOCHONDRIA

Por Durphy, Michael, Manley, Paul N., Friedberg, Errol C.
Publicado em 1974

Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog

Por Boggon, Titus J., Li, Yiqun, Manley, Paul W., Eck, Michael J.
Publicado em 2005

Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2

Por Ammoun, Sylwia, Schmid, Marei Caroline, Triner, Joceline, Manley, Paul, Hanemann, Clemens Oliver
Publicado em 2011

Hamstring Graft Technique for Stabilization of Canine Cranial Cruciate Ligament Deficient Stifles

Por LOPEZ, MANDI J., MARKEL, MARK D., KALSCHEUR, VICKI, LU, YAN, MANLEY, PAUL A.
Publicado em 2003

Synthesis and characterization of a novel tritiated K(ATP) channel opener with a benzopyran structure

Por Manley, Paul W, Löffler-Walz, Cornelia, Russ, Ulrich, Hambrock, Annette, Moenius, Thomas, Quast, Ulrich
Publicado em 2001

One bite or two? A prospective trial comparing colonoscopy biopsy technique in patients with chronic ulcerative colitis

Por Hookey, Lawrence C, Hurlbut, David J, Day, Andrew G, Manley, Paul N, Depew, William T
Publicado em 2007

Imatinib relaxes the pulmonary venous bed of guinea pigs

Por Maihöfer, Nina A., Suleiman, Said, Dreymüller, Daniela, Manley, Paul W., Rossaint, Rolf, Uhlig, Stefan, Martin, Christian, Rieg, Annette D.
Publicado no Respir Res (2017)

Erratum to: Imatinib relaxes the pulmonary venous bed of guinea pigs

Por Maihöfer, Nina A., Suleiman, Said, Dreymüller, Daniela, Manley, Paul W., Rossaint, Rolf, Uhlig, Stefan, Martin, Christian, Rieg, Annette D.
Publicado no Respir Res (2017)

Imaging the Intracellular Distribution of Tyrosine Kinase Inhibitors in Living Cells with Quantitative Hyperspectral Stimulated Raman Scattering

Por Fu, Dan, Zhou, Jing, Zhu, Wenjing Suzanne, Manley, Paul W., Wang, Y. Karen, Hood, Tami, Wylie, Andrew, Xie, X. Sunney
Publicado em 2014

Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib: Potentiation of nilotinib by CXCR4 antagonist

Por Weisberg, Ellen, Azab, Abdel Kareem, Manley, Paul W., Kung, Andrew L., Christie, Amanda L., Bronson, Rod, Ghobrial, Irene M., Griffin, James D.
Publicado em 2011

Nilotinib Is More Potent than Imatinib for Treating Plexiform Neurofibroma In Vitro and In Vivo

Por Wei, Jiang, Freytag, Marcus, Schober, Yvonne, Nockher, Wolfgang A., Mautner, Victor F., Friedrich, Reinhard E., Manley, Paul W., Kluwe, Lan, Kurtz, Andreas
Publicado em 2014

Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia

Por Cowan-Jacob, Sandra W., Fendrich, Gabriele, Floersheimer, Andreas, Furet, Pascal, Liebetanz, Janis, Rummel, Gabriele, Rheinberger, Paul, Centeleghe, Mario, Fabbro, Doriano, Manley, Paul W.
Publicado em 2006

Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison

Por Weisberg, Ellen, Roesel, Johannes, Furet, Pascal, Bold, Guido, Imbach, Patricia, Flörsheimer, Andreas, Caravatti, Georgio, Jiang, Jingrui, Manley, Paul, Ray, Arghya, Griffin, James D.
Publicado em 2010

Effects of PKC412, nilotinib and imatinib against GIST-associated PDGFRA mutants with differential imatinib sensitivity: Mutant PDGFRA: PKC412, nilotinib, imatinib

Por Weisberg, Ellen, Wright, Renee D., Jiang, Jingrui, Ray, Arghya, Moreno, Daisy, Manley, Paul W., Fabbro, Doriano, Hall-Meyers, Elizabeth, Catley, Laurie, Podar, Klaus, Kung, Andrew L., Griffin, James D.
Publicado em 2006

The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRβ and FIP1L1-PDGFRα in vitro and in vivo

Por Stover, Elizabeth H., Chen, Jing, Lee, Benjamin H., Cools, Jan, McDowell, Elizabeth, Adelsperger, Jennifer, Cullen, Dana, Coburn, Allison, Moore, Sandra A., Okabe, Rachel, Fabbro, Doriano, Manley, Paul W., Griffin, James D., Gilliland, D. Gary
Publicado em 2005

A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” mutant of Bcr-Abl

Por Choi, Hwan Geun, Ren, Pingda, Adrian, Francisco, Sun, Fangxian, Lee, Hyun Soo, Wang, Xia, Ding, Qiang, Zhang, Guobao, Zhang, Yongping, Liu, Yi, Tuntland, Tove, Warmuth, Markus, Manley, Paul W., Mestan, Jürgen, Gray, Nathanael S, Sim, Taebo
Publicado em 2010

KIT signaling governs differential sensitivity of mature and primitive CML progenitors to tyrosine kinase inhibitors

Por Corbin, Amie S., O’Hare, Thomas, Gu, Zhimin, Kraft, Ira L., Eiring, Anna M., Khorashad, Jamshid S., Pomicter, Anthony D., Zhang, Tian Y., Eide, Christopher A., Manley, Paul W., Cortes, Jorge E., Druker, Brian J., Deininger, Michael W.
Publicado em 2013

Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia

Por Irvine, David A., Zhang, Bin, Kinstrie, Ross, Tarafdar, Anuradha, Morrison, Heather, Campbell, Victoria L., Moka, Hothri A., Ho, Yinwei, Nixon, Colin, Manley, Paul W., Wheadon, Helen, Goodlad, John R., Holyoake, Tessa L., Bhatia, Ravi, Copland, Mhairi
Publicado no Sci Rep (2016)

Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL(+) leukemias

Por Weisberg, Ellen, Catley, Laurie, Wright, Renee D., Moreno, Daisy, Banerji, Lolita, Ray, Arghya, Manley, Paul W., Mestan, Juergen, Fabbro, Doriano, Jiang, Jingrui, Hall-Meyers, Elizabeth, Callahan, Linda, DellaGatta, Jamie L., Kung, Andrew L., Griffin, James D.
Publicado em 2007