The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRβ and FIP1L1-PDGFRα in vitro and in vivo

AMN107 is a small molecule tyrosine kinase inhibitor developed, in the first instance, as a potent inhibitor of breakpoint cluster region-abelson (BCR-ABL). We tested its effectiveness against fusion tyrosine kinases TEL–platelet-derived growth factor receptorβ (TEL-PDGFRβ) and FIP1-like-1 (FIP1L1)–...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Stover, Elizabeth H., Chen, Jing, Lee, Benjamin H., Cools, Jan, McDowell, Elizabeth, Adelsperger, Jennifer, Cullen, Dana, Coburn, Allison, Moore, Sandra A., Okabe, Rachel, Fabbro, Doriano, Manley, Paul W., Griffin, James D., Gilliland, D. Gary
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2005 by The American Society of Hematology 2005
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895333/
https://ncbi.nlm.nih.gov/pubmed/16030188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1932
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky