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Imatinib relaxes the pulmonary venous bed of guinea pigs
BACKGROUND: Recently, the IMPRES study revealed that systemic imatinib improves exercise capacity in patients with advanced pulmonary arterial hypertension. Imatinib blocks the tyrosine kinase activity of the platelet-derived growth factor (PDGF)-receptor (PDGFR), acts antiproliferative and relaxes...
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| Publicado no: | Respir Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5299687/ https://ncbi.nlm.nih.gov/pubmed/28178968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0514-0 |
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