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Synthesis and characterization of a novel tritiated K(ATP) channel opener with a benzopyran structure

1. The synthesis of a tritiated benzopyran-type opener of the ATP-dependent K(+) channel (K(ATP) channel), [(3)H]-PKF217 – 744 {(3S,4R)-N-[3,4-dihydro-2,2-dimethyl-3-hydroxy-6-(2-methyl-4-pyridinyl)-2H-1-benzopyran-4-yl]-3-[2,6-(3)H]pyridinecarboxamide} with a specific activity of 50 Ci mmol(−1) is...

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Détails bibliographiques
Auteurs principaux: Manley, Paul W, Löffler-Walz, Cornelia, Russ, Ulrich, Hambrock, Annette, Moenius, Thomas, Quast, Ulrich
Format: Artigo
Langue:Inglês
Publié: 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572780/
https://ncbi.nlm.nih.gov/pubmed/11350864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704071
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