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Mg(2+) sensitizes K(ATP) channels to inhibition by DIDS: dependence on the sulphonylurea receptor subunit
1. ATP-sensitive potassium channels (K(ATP) channels) consist of pore-forming Kir6.x subunits and of sulphonylurea receptors (SURs). In the absence of Mg(2+), the stilbene disulphonate, DIDS, irreversibly inhibits K(ATP) channels by binding to the Kir subunit. Here, the effects of Mg(2+) on the inte...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573525/ https://ncbi.nlm.nih.gov/pubmed/12359624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704905 |
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