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Mg(2+) sensitizes K(ATP) channels to inhibition by DIDS: dependence on the sulphonylurea receptor subunit

1. ATP-sensitive potassium channels (K(ATP) channels) consist of pore-forming Kir6.x subunits and of sulphonylurea receptors (SURs). In the absence of Mg(2+), the stilbene disulphonate, DIDS, irreversibly inhibits K(ATP) channels by binding to the Kir subunit. Here, the effects of Mg(2+) on the inte...

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Bibliografische gegevens
Hoofdauteurs: Gojkovic-Bukarica, Ljiljana, Hambrock, Annette, Löffler-Walz, Cornelia, Quast, Ulrich, Russ, Ulrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573525/
https://ncbi.nlm.nih.gov/pubmed/12359624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704905
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