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Interaction of a novel dihydropyridine K(+) channel opener, A-312110, with recombinant sulphonylurea receptors and K(ATP) channels: comparison with the cyanoguanidine P1075
1. ATP-sensitive K(+) channels (K(ATP) channels) are composed of pore-forming subunits (Kir6.x) and of regulatory subunits, the sulphonylurea receptors (SURx). Synthetic openers of K(ATP) channels form a chemically heterogeneous class of compounds that are of interest in several therapeutic areas. W...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574886/ https://ncbi.nlm.nih.gov/pubmed/15023854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705718 |
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