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Binding of K(ATP) channel modulators in rat cardiac membranes
1. The binding of [(3)H]-P1075, a potent opener of adenosine-5′-triphosphate-(ATP)-sensitive K(+) channels, was studied in a crude heart membrane preparation of the rat, at 37°C. 2. Binding required MgATP. In the presence of an ATP-regenerating system, MgATP supported [(3)H]-P1075 binding with an EC...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565308/ https://ncbi.nlm.nih.gov/pubmed/9579735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701756 |
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