Mutasynthesis of Fluorinated Pactamycin Analogs and Their Antimalarial Activity

Bằng Almabruk, Khaled H., Lu, Wanli, Li, Yuexin, Abugreen, Mostafa, Kelly, Jane X., Mahmud, Taifo
Được phát hành 2013

Total Synthesis and Antimalarial Activity of 2-(p-Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria

Bằng Kancharla, Papireddy, Li, Yuexin, Yeluguri, Monish, Dodean, Rozalia A., Reynolds, Kevin A., Kelly, Jane X.
Xuất bản năm J Med Chem (2021)

Antimalarial Quinolones: Synthesis, potency, and mechanistic studies

Bằng Winter, Rolf W., Kelly, Jane X., Smilkstein, Martin J., Dodean, Rozalia, Hinrichs, David, Riscoe, Michael K.
Được phát hành 2007

Optimization of endochin-like quinolones for antimalarial activity

Bằng Winter, Rolf, Kelly, Jane X., Smilkstein, Martin J., Hinrichs, David, Koop, Dennis R., Riscoe, Michael K.
Được phát hành 2010

Synthesis, Structure-Activity Relationship, & Mode-of-Action Studies of Antimalarial Reversed Chloroquine Compounds

Bằng Burgess, Steven J., Kelly, Jane X., Shomloo, Shawheen, Wittlin, Sergio, Brun, Reto, Liebmann, Katherine, Peyton, David H.
Được phát hành 2010

Selective Killing of the Human Malaria Parasite Plasmodium falciparum by a Benzylthiazolium dye

Bằng Kelly, Jane X., Winter, Rolf W., Braun, Theodore P., Osei-Agyemang, Myralyn, Hinrichs, David J., Riscoe, Michael K.
Được phát hành 2006

Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs

Bằng Gunsaru, Bornface, Burgess, Steven J., Morrill, Westin, Kelly, Jane X., Shomloo, Shawheen, Smilkstein, Martin J., Liebman, Katherine, Peyton, David H.
Xuất bản năm Antimicrob Agents Chemother (2017)

Unsymmetrical Bisquinolines with High Potency against P. falciparum Malaria

Bằng Liebman, Katherine M., Burgess, Steven J., Gunsaru, Bornface, Kelly, Jane X., Li, Yuexin, Morrill, Westin, Liebman, Michael C., Peyton, David H.
Xuất bản năm Molecules (2020)

Acridones are Highly Potent Inhibitors of Toxoplasma gondii Tachyzoites

Bằng Alday, P. Holland, McConnell, Erin V., Boitz Zarella, Jan M., Dodean, Rozalia A., Kancharla, Papireddy, Kelly, Jane X., Doggett, J. Stone
Xuất bản năm ACS Infect Dis (2021)

Design, Synthesis, and Evaluation of 10-N-Substituted Acridones as Novel Chemosensitizers in Plasmodium falciparum

Bằng Kelly, Jane X., Smilkstein, Martin J., Cooper, Roland A., Lane, Kristin D., Johnson, Robert A., Janowsky, Aaron, Dodean, Rozalia A., Hinrichs, David J., Winter, Rolf, Riscoe, Michael
Được phát hành 2007

Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc(1) Inhibition Strategy for Malaria

Bằng Stickles, Allison M., Smilkstein, Martin J., Morrisey, Joanne M., Li, Yuexin, Forquer, Isaac P., Kelly, Jane X., Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Vaidya, Akhil B., Riscoe, Michael K.
Xuất bản năm Antimicrob Agents Chemother (2016)

Depsipeptide Companeramides from a Panamanian Marine Cyanobacterium Associated with the Coibamide Producer

Bằng Vining, Oliver B., Medina, Rebecca A., Mitchell, Edward A., Videau, Patrick, Li, Dong, Serrill, Jeffrey D., Kelly, Jane X., Gerwick, William H., Proteau, Philip J., Ishmael, Jane E., McPhail, Kerry L.
Xuất bản năm J Nat Prod (2015)

Discovery of Dual Function Acridones as a Novel Antimalarial Chemotype

Bằng Kelly, Jane X., Smilkstein, Martin J., Brun, Reto, Wittlin, Sergio, Cooper, Roland A., Lane, Kristin D., Janowsky, Aaron, Johnson, Robert A., Dodean, Rozalia A., Winter, Rolf, Hinrichs, David J., Riscoe, Michael K.
Xuất bản năm Nature (2009)

Diphenylether-modified 1,2-diamines with improved drug properties for development against Mycobacterium tuberculosis

Bằng Foss, Marie H., Pou, Sovitj, Davidson, Patrick M., Dunaj, Jennifer L., Winter, Rolf W., Pou, Sovijja, Licon, Meredith H., Doh, Julia K., Li, Yuexin, Kelly, Jane X., Dodean, Rozalia A., Koop, Dennis R., Riscoe, Michael K., Purdy, Georgiana E.
Xuất bản năm ACS Infect Dis (2016)

Inhibition of Cytochrome bc(1) as a Strategy for Single-Dose, Multi-Stage Antimalarial Therapy

Bằng Stickles, Allison M., Ting, Li-Min, Morrisey, Joanne M., Li, Yuexin, Mather, Michael W., Meermeier, Erin, Pershing, April M., Forquer, Isaac P., Miley, Galen P., Pou, Sovitj, Winter, Rolf W., Hinrichs, David J., Kelly, Jane X., Kim, Kami, Vaidya, Akhil B., Riscoe, Michael K., Nilsen, Aaron
Xuất bản năm Am J Trop Med Hyg (2015)

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria

Bằng Frueh, Lisa, LI, Yuexin, Mather, Michael W., Li, Qigui, Pou, Sovitj, Nilsen, Aaron, Winter, Rolf W., Forquer, Isaac P., Pershing, April M., Xie, Lisa H., Smilkstein, Martin J., Caridha, Diana, Campbell, Robert F., Sciotti, Richard J., Kreishman-Deitrick, Mara, Kelly, Jane X., Vesely, Brian, Vaidya, Akhil B., Riscoe, Michael K
Xuất bản năm ACS Infect Dis (2017)

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Bằng Smilkstein, Martin J., Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A., Dodean, Rozalia A., Frueh, Lisa, Hinrichs, David J., Li, Yuexin, Martinson, Thomas, Munar, Myrna Y., Winter, Rolf W., Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R., Kelly, Jane X., Kappe, Stefan H. I., Wilder, Brandon K., Riscoe, Michael K.
Xuất bản năm Malar J (2019)

ELQ-300 Prodrugs for Enhanced Delivery and Single-Dose Cure of Malaria

Bằng Miley, Galen P., Pou, Sovitj, Winter, Rolf, Nilsen, Aaron, Li, Yuexin, Kelly, Jane X., Stickles, Allison M., Mather, Michael W., Forquer, Isaac P., Pershing, April M., White, Karen, Shackleford, David, Saunders, Jessica, Chen, Gong, Ting, Li-Min, Kim, Kami, Zakharov, Lev N., Donini, Cristina, Burrows, Jeremy N., Vaidya, Akhil B., Charman, Susan A., Riscoe, Michael K.
Xuất bản năm Antimicrob Agents Chemother (2015)

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials

Bằng Dodean, Rozalia A., Kancharla, Papireddy, Li, Yuexin, Melendez, Victor, Read, Lisa, Bane, Charles E., Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J., Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E., Nolan, Christina, Huezo, Stephanie J., Rasmussen, Stephanie A., Stephens, Melissa T., Tan, John C., Cooper, Roland A., Smilkstein, Martin J., Pou, Sovitj, Winter, Rolf W., Riscoe, Michael K., Kelly, Jane X.
Xuất bản năm J Med Chem (2019)

Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials

Bằng Kancharla, Papireddy, Dodean, Rozalia A., Li, Yuexin, Pou, Sovitj, Pybus, Brandon, Melendez, Victor, Read, Lisa, Bane, Charles E., Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J., Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E., Nolan, Christina, Ceja, Frida G., Rasmussen, Stephanie A., Tumwebaze, Patrick K., Rosenthal, Philip J., Mu, Jianbing, Bayles, Brett R., Cooper, Roland A., Reynolds, Kevin A., Smilkstein, Martin J., Riscoe, Michael K., Kelly, Jane X.
Xuất bản năm J Med Chem (2020)