Alcohol Metabolism’s Damaging Effects on the Cell: A Focus on Reactive Oxygen Generation by the Enzyme Cytochrome P450 2E1

Por Koop, Dennis R.
Publicado no Alcohol Res Health (2006)

Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry

Por Koop, Dennis R., Bleyle, Lisa A., Munar, Myrna, Cherala, Ganesh, Al-Uzri, Amira
Publicado em 2013

The Effects of Nitrogen-Heme-Iron Coordination on Substrate Affinities for Cytochrome P450 2E1.

Por Jones, Jeffrey P., Joswig-Jones, Carolyn A., Hebner, Michelle, Chu, Yuzhuo, Koop, Dennis R.
Publicado em 2011

Optimization of endochin-like quinolones for antimalarial activity

Por Winter, Rolf, Kelly, Jane X., Smilkstein, Martin J., Hinrichs, David, Koop, Dennis R., Riscoe, Michael K.
Publicado em 2010

Paired Assessment of Volatile Anesthetic Concentrations with Synaptic Actions Recorded In Vitro

Por McDougall, Stuart J., Peters, James H., LaBrant, Lia, Wang, Xin, Koop, Dennis R., Andresen, Michael C.
Publicado em 2008

Ubiquitin-dependent Proteasomal Degradation of Human Liver Cytochrome P450 2E1: IDENTIFICATION OF SITES TARGETED FOR PHOSPHORYLATION AND UBIQUITINATION

Por Wang, YongQiang, Guan, Shenheng, Acharya, Poulomi, Koop, Dennis R., Liu, Yi, Liao, Mingxiang, Burlingame, Alma L., Correia, Maria Almira
Publicado em 2011

Pharmacokinetic study of lipoic acid in multiple sclerosis: Comparing mice and human pharmacokinetic parameters

Por Yadav, Vijayshree, Marracci, Gail H., Munar, Myrna Y., Cherala, Ganesh, Stuber, Lauren E., Alvarez, Lilia, Shinto, Lynne, Koop, Dennis R., Bourdette, Dennis N.
Publicado em 2010

Intestinal metabolites are profoundly altered in the context of HLA-B27 expression and functionally modulate disease in a rat model of spondyloarthropathy

Por Asquith, Mark, Davin, Sean, Stauffer, Patrick, Michell, Claire, Janowitz, Cathleen, Lin, Phoebe, Ensign-Lewis, Joe, Kinchen, Jason M., Koop, Dennis R, Rosenbaum, James T.
Publicado no Arthritis Rheumatol (2017)

Soluble Epoxide Hydrolase Gene Deletion Is Protective Against Experimental Cerebral Ischemia

Por Zhang, Wenri, Otsuka, Takashi, Sugo, Nobuo, Ardeshiri, Ardi, Alhadid, Yazan K., Iliff, Jeffrey J., DeBarber, Andrea E., Koop, Dennis R., Alkayed, Nabil J.
Publicado em 2008

Mechanism for Prevention of Alcohol-Induced Liver Injury by Dietary Methyl Donors

Por Powell, Christine L., Bradford, Blair U., Craig, Christopher Patrick, Tsuchiya, Masato, Uehara, Takeki, O’Connell, Thomas M., Pogribny, Igor P., Melnyk, Stepan, Koop, Dennis R., Bleyle, Lisa, Threadgill, David W., Rusyn, Ivan
Publicado em 2010

Interstrain Differences in the Liver Effects of Trichloroethylene in a Multistrain Panel of Inbred Mice

Por Bradford, Blair U., Lock, Eric F., Kosyk, Oksana, Kim, Sungkyoon, Uehara, Takeki, Harbourt, David, DeSimone, Michelle, Threadgill, David W., Tryndyak, Volodymyr, Pogribny, Igor P., Bleyle, Lisa, Koop, Dennis R., Rusyn, Ivan
Publicado em 2011

A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer

Por Alumkal, Joshi J., Slottke, Rachel, Schwartzman, Jacob, Cherala, Ganesh, Munar, Myrna, Graff, Julie N., Beer, Tomasz M., Ryan, Christopher W., Koop, Dennis R., Gibbs, Angela, Gao, Lina, Flamiatos, Jason F., Tucker, Erin, Kleinschmidt, Richard, Mori, Motomi
Publicado no Invest New Drugs (2014)

Diphenylether-modified 1,2-diamines with improved drug properties for development against Mycobacterium tuberculosis

Por Foss, Marie H., Pou, Sovitj, Davidson, Patrick M., Dunaj, Jennifer L., Winter, Rolf W., Pou, Sovijja, Licon, Meredith H., Doh, Julia K., Li, Yuexin, Kelly, Jane X., Dodean, Rozalia A., Koop, Dennis R., Riscoe, Michael K., Purdy, Georgiana E.
Publicado no ACS Infect Dis (2016)

Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells define commitment to apoptosis

Por O’Hare, Thomas, Eide, Christopher A., Agarwal, Anupriya, Adrian, Lauren T., Zabriskie, Matthew S., MacKenzie, Ryan J., LaTocha, Dorian H., Johnson, Kara J., You, Huihong, Luo, Jenny, Riddle, Steven M., Marks, Bryan D., Vogel, Kurt W., Koop, Dennis R., Apgar, John, Tyner, Jeffrey W., Deininger, Michael W., Druker, Brian J.
Publicado em 2013

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Por Smilkstein, Martin J., Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A., Dodean, Rozalia A., Frueh, Lisa, Hinrichs, David J., Li, Yuexin, Martinson, Thomas, Munar, Myrna Y., Winter, Rolf W., Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R., Kelly, Jane X., Kappe, Stefan H. I., Wilder, Brandon K., Riscoe, Michael K.
Publicado no Malar J (2019)