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Soluble Epoxide Hydrolase Gene Deletion Is Protective Against Experimental Cerebral Ischemia
BACKGROUND AND PURPOSE: Cytochrome P450 epoxygenase metabolizes arachidonic acid to epoxyeicosatrienoic acids (EETs). EETs are produced in the brain and perform important biological functions, including vasodilation and neuroprotection. However, EETs are rapidly metabolized via soluble epoxide hydro...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654189/ https://ncbi.nlm.nih.gov/pubmed/18369166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.107.508325 |
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