Apolipoprotein E knockout rabbit model of intracranial atherosclerotic disease

Tekijä Zabriskie, Matthew S., Wang, Chuanzhuo, Wang, Shuping, Alexander, Matthew D.
Julkaisussa Animal Model Exp Med (2020)

Radotinib is an Effective Inhibitor of Native and Kinase Domain-Mutant BCR-ABL1

Tekijä Zabriskie, Matthew S., Vellore, Nadeem A., Gantz, Kevin C., Deininger, Michael W., O’Hare, Thomas
Julkaisussa Leukemia (2015)

Limited efficacy of BMS-911543 in a murine model of Janus kinase 2 V617F myeloproliferative neoplasm

Tekijä Pomicter, Anthony D., Eiring, Anna M., Senina, Anna V., Zabriskie, Matthew S., Marvin, James E., Prchal, Josef T., O’Hare, Thomas, Deininger, Michael W.
Julkaisussa Exp Hematol (2015)

Rabbit models of intracranial atherosclerotic disease for pathological validation of vessel wall MRI

Tekijä McNally, J Scott, de Havenon, Adam, Kim, Seong-Eun, Wang, Chuanzhuo, Wang, Shuping, Zabriskie, Matthew S, Parker, Dennis L, Baradaran, Hediyeh, Alexander, Matthew D
Julkaisussa Neuroradiol J (2020)

A Coiled-Coil Mimetic Intercepts BCR-ABL1 Dimerization in Native and Kinase-Mutant Chronic Myeloid Leukemia

Tekijä Woessner, David W., Eiring, Anna M., Bruno, Benjamin J., Zabriskie, Matthew S., Reynolds, Kimberly R., Miller, Geoffrey D., O’Hare, Thomas, Deininger, Michael W., Lim, Carol S.
Julkaisussa Leukemia (2015)

Mechanisms of Resistance to the BCR-ABL1 Allosteric Inhibitor Asciminib

Tekijä Qiang, Wang, Antelope, Orlando, Zabriskie, Matthew S., Pomicter, Anthony D., Vellore, Nadeem A., Szankasi, Philippe, Rea, Delphine, Cayuela, Jean Michel, Kelley, Todd W., Deininger, Michael W., O’Hare, Thomas
Julkaisussa Leukemia (2017)

Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia

Tekijä Packer, Leisl M., Rana, Sareena, Hayward, Robert, O'Hare, Thomas, Eide, Christopher A., Rebocho, Ana, Heidorn, Sonja, Zabriskie, Matthew S., Niculescu-Duvaz, Ion, Druker, Brian J., Springer, Caroline, Marais, Richard
Julkaistu 2011

The BCR-ABL(35INS) insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Tekijä O'Hare, Thomas, Zabriskie, Matthew S., Eide, Christopher A., Agarwal, Anupriya, Adrian, Lauren T., You, Huihong, Corbin, Amie S., Yang, Fei, Press, Richard D., Rivera, Victor M., Toplin, Julie, Wong, Stephane, Deininger, Michael W., Druker, Brian J.
Julkaistu 2011

A novel crizotinib-resistant solvent-front mutation responsive to cabozantinib therapy in a patient with ROS1-rearranged lung cancer

Tekijä Drilon, Alexander, Somwar, Romel, Wagner, Jacob. P., Vellore, Nadeem. A., Eide, Christopher A., Zabriskie, Matthew. S., Arcila, Maria. E., Hechtman, Jaclyn F., Wang, Lu, Smith, Roger S., Kris, Mark. G., Riely, Gregory. J., Druker, Brian. J., O’Hare, Thomas, Ladanyi, Marc., Davare, Monika. A.
Julkaisussa Clin Cancer Res (2015)

A novel AGGF1-PDGFRb fusion in pediatric T-cell acute lymphoblastic leukemia

Tekijä Zabriskie, Matthew S., Antelope, Orlando, Verma, Anupam R., Draper, Lauren R., Eide, Christopher A., Pomicter, Anthony D., Tran, Thai Hoa, Druker, Brian J., Tyner, Jeffrey W., Miles, Rodney R., Graham, James M., Hwang, Jae-Yeon, Varley, Katherine E., Toydemir, Reha M., Deininger, Michael W., Raetz, Elizabeth A., O’Hare, Thomas
Julkaisussa Haematologica (2018)

Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells define commitment to apoptosis

Tekijä O’Hare, Thomas, Eide, Christopher A., Agarwal, Anupriya, Adrian, Lauren T., Zabriskie, Matthew S., MacKenzie, Ryan J., LaTocha, Dorian H., Johnson, Kara J., You, Huihong, Luo, Jenny, Riddle, Steven M., Marks, Bryan D., Vogel, Kurt W., Koop, Dennis R., Apgar, John, Tyner, Jeffrey W., Deininger, Michael W., Druker, Brian J.
Julkaistu 2013

shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance

Tekijä Khorashad, Jamshid S., Eiring, Anna M., Mason, Clinton C., Gantz, Kevin C., Bowler, Amber D., Redwine, Hannah M., Yu, Fan, Kraft, Ira L., Pomicter, Anthony D., Reynolds, Kimberly R., Iovino, Anthony J., Zabriskie, Matthew S., Heaton, William L., Tantravahi, Srinivas K., Kauffman, Michael, Shacham, Sharon, Chenchik, Alex, Bonneau, Kyle, Ullman, Katharine S., O’Hare, Thomas, Deininger, Michael W.
Julkaisussa Blood (2015)

BCR-ABL1 compound mutations in tyrosine kinase inhibitor–resistant CML: frequency and clonal relationships

Tekijä Khorashad, Jamshid S., Kelley, Todd W., Szankasi, Philippe, Mason, Clinton C., Soverini, Simona, Adrian, Lauren T., Eide, Christopher A., Zabriskie, Matthew S., Lange, Thoralf, Estrada, Johanna C., Pomicter, Anthony D., Eiring, Anna M., Kraft, Ira L., Anderson, David J., Gu, Zhimin, Alikian, Mary, Reid, Alistair G., Foroni, Letizia, Marin, David, Druker, Brian J., O'Hare, Thomas, Deininger, Michael W.
Julkaistu 2013

Combined STAT3 and BCR-ABL1 Inhibition Induces Synthetic Lethality in Therapy-Resistant Chronic Myeloid Leukemia

Tekijä Eiring, Anna M., Page, Brent D. G., Kraft, Ira L., Mason, Clinton C., Vellore, Nadeem A., Resetca, Diana, Zabriskie, Matthew S., Zhang, Tian Y., Khorashad, Jamshid S., Engar, Alexander J., Reynolds, Kimberly R., Anderson, David J., Senina, Anna, Pomicter, Anthony D., Arpin, Carolynn C., Ahmad, Shazia, Heaton, William L., Tantravahi, Srinivas K., Todic, Aleksandra, Moriggl, Richard, Wilson, Derek J., Baron, Riccardo, O'Hare, Thomas, Gunning, Patrick T., Deininger, Michael W.
Julkaisussa Leukemia (2014)

Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy Against Highly Resistant BCR-ABL1 Mutants

Tekijä Eide, Christopher A., Zabriskie, Matthew S., Savage Stevens, Samantha L., Antelope, Orlando, Vellore, Nadeem A., Than, Hein, Schultz, Anna Reister, Clair, Phillip, Bowler, Amber D., Pomicter, Anthony D., Yan, Dongqing, Senina, Anna V., Qiang, Wang, Kelley, Todd W., Szankasi, Philippe, Heinrich, Michael C., Tyner, Jeffrey W., Rea, Delphine, Cayuela, Jean-Michel, Kim, Dong-Wook, Tognon, Cristina E., O’Hare, Thomas, Druker, Brian J., Deininger, Michael W.
Julkaisussa Cancer Cell (2019)

SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Tekijä Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D., Halverson, Brayden J., Antelope, Orlando, Mason, Clinton C., Ahmann, Jonathan M., Senina, Anna V., Vellore, Nadeem A., Jones, Courtney L., Zabriskie, Matthew S., Than, Hein, Xiao, Michael J., van Scoyk, Alexandria, Patel, Ami B., Clair, Phillip M., Heaton, William L., Owen, Shawn C., Andersen, Joshua L., Egbert, Christina M., Reisz, Julie A., D'Alessandro, Angelo, Cox, James E., Gantz, Kevin C., Redwine, Hannah M., Iyer, Siddharth M., Khorashad, Jamshid S., Rajabi, Nima, Olsen, Christian A., O'Hare, Thomas, Deininger, Michael W.
Julkaisussa Blood Cancer Discov (2021)

BCR-ABL1 Compound Mutations Combining Key Kinase Domain Positions Confer Clinical Resistance to Ponatinib in Ph Chromosome-Positive Leukemia

Tekijä Zabriskie, Matthew S., Eide, Christopher A., Tantravahi, Srinivas K., Vellore, Nadeem A., Estrada, Johanna, Nicolini, Franck E., Khoury, Hanna J., Larson, Richard A., Konopleva, Marina, Cortes, Jorge E., Kantarjian, Hagop, Jabbour, Elias J., Kornblau, Steven M., Lipton, Jeffrey H., Rea, Delphine, Stenke, Leif, Barbany, Gisela, Lange, Thoralf, Hernández-Boluda, Juan-Carlos, Ossenkoppele, Gert J., Press, Richard D., Chuah, Charles, Goldberg, Stuart L., Wetzler, Meir, Mahon, Francois-Xavier, Etienne, Gabriel, Baccarani, Michele, Soverini, Simona, Rosti, Gianantonio, Rousselot, Philippe, Friedman, Ran, Deininger, Marie, Reynolds, Kimberly R., Heaton, William L., Eiring, Anna M., Pomicter, Anthony D., Khorashad, Jamshid S., Kelley, Todd W., Baron, Riccardo, Druker, Brian J., Deininger, Michael W., O'Hare, Thomas
Julkaistu 2014