ELQ-331 as a prototype for extremely durable chemoprotection against malaria

BACKGROUND: The potential benefits of long-acting injectable chemoprotection (LAI-C) against malaria have been recently recognized, prompting a call for suitable candidate drugs to help meet this need. On the basis of its known pharmacodynamic and pharmacokinetic profiles after oral dosing, ELQ-331,...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Smilkstein, Martin J., Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A., Dodean, Rozalia A., Frueh, Lisa, Hinrichs, David J., Li, Yuexin, Martinson, Thomas, Munar, Myrna Y., Winter, Rolf W., Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R., Kelly, Jane X., Kappe, Stefan H. I., Wilder, Brandon K., Riscoe, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712883/
https://ncbi.nlm.nih.gov/pubmed/31455339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2921-9
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