Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo

ανά Wood, Warren J. L., Geraci, Travis, Nilsen, Aaron, DeBarber, Andrea E., Scanlan, Thomas S.
Έκδοση 2009

Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

ανά Eshleman, Amy J, Nagarajan, Shanthi, Wolfrum, Katherine M, Reed, John F, Swanson, Tracy L, Nilsen, Aaron, Janowsky, Aaron
Τόπος έκδοσης Psychopharmacology (Berl) (2018)

Genetic Evidence for Cytochrome b Q(i) Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii

ανά Alday, P. Holland, Bruzual, Igor, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Ben Mamoun, Choukri, Riscoe, Michael K., Doggett, J. Stone
Τόπος έκδοσης Antimicrob Agents Chemother (2017)

Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil

ανά van Schalkwyk, Donelly A., Riscoe, Michael K., Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Duffey, Maëlle, Moon, Robert W., Sutherland, Colin J.
Τόπος έκδοσης Antimicrob Agents Chemother (2020)

Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems

ανά Potharaju, Suresh, Mutyam, Shravan Kumar, Liu, Mingtao, Green, Carol, Frueh, Lisa, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Riscoe, Michael K., Shankar, Gita
Τόπος έκδοσης Pharm Dev Technol (2020)

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

ανά Ke, Hangjun, Ganesan, Suresh M., Dass, Swati, Morrisey, Joanne M., Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael K., Mather, Michael W., Vaidya, Akhil B.
Τόπος έκδοσης PLoS One (2019)

Targeting the Cytochrome bc(1) Complex of Leishmania Parasites for Discovery of Novel Drugs

ανά Ortiz, Diana, Forquer, Isaac, Boitz, Jan, Soysa, Radika, Elya, Carolyn, Fulwiler, Audrey, Nilsen, Aaron, Polley, Tamsen, Riscoe, Michael K., Ullman, Buddy, Landfear, Scott M.
Τόπος έκδοσης Antimicrob Agents Chemother (2016)

Endochin-Like Quinolones Exhibit Promising Efficacy Against Neospora Caninum in vitro and in Experimentally Infected Pregnant Mice

ανά Anghel, Nicoleta, Balmer, Vreni, Müller, Joachim, Winzer, Pablo, Aguado-Martinez, Adriana, Roozbehani, Mona, Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael, Doggett, J. Stone, Hemphill, Andrew
Τόπος έκδοσης Front Vet Sci (2018)

Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity

ανά Rozanov, Dmitri, Cheltsov, Anton, Nilsen, Aaron, Boniface, Christopher, Forquer, Isaac, Korkola, James, Gray, Joe, Tyner, Jeffrey, Tognon, Cristina E., Mills, Gordon B., Spellman, Paul
Τόπος έκδοσης PLoS One (2019)

Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi

ανά Silva, Marta G., Bastos, Reginaldo G., Stone Doggett, J., Riscoe, Michael K., Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A., Nilsen, Aaron, Suarez, Carlos E.
Τόπος έκδοσης Parasit Vectors (2020)

Activities of Endochin-Like Quinolones Against in vitro Cultured Besnoitia besnoiti Tachyzoites

ανά Eberhard, Naja, Balmer, Vreni, Müller, Joachim, Müller, Norbert, Winter, Rolf, Pou, Soviti, Nilsen, Aaron, Riscoe, Mike, Francisco, Samuel, Leitao, Alexandre, Doggett, J. Stone, Hemphill, Andrew
Τόπος έκδοσης Front Vet Sci (2020)

Sontochin as a Guide to the Development of Drugs against Chloroquine-Resistant Malaria

ανά Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Kelly, Jane Xu, Li, Yuexin, Doggett, J. Stone, Riscoe, Erin W., Wegmann, Keith W., Hinrichs, David J., Riscoe, Michael K.
Έκδοση 2012

Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

ανά Doggett, J. Stone, Schultz, Tracey, Miller, Alyssa J., Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia, Zakharov, Lev N., Nilsen, Aaron, Riscoe, Michael K., Carruthers, Vern B.
Τόπος έκδοσης Antimicrob Agents Chemother (2020)

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc(1) and Identi...

ανά McConnell, Erin V., Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A., Smilkstein, Martin J., Krollenbrock, Alina, Nilsen, Aaron, Zakharov, Lev N., Riscoe, Michael K., Doggett, J. Stone
Τόπος έκδοσης ACS Infect Dis (2018)

Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc(1) Inhibition Strategy for Malaria

ανά Stickles, Allison M., Smilkstein, Martin J., Morrisey, Joanne M., Li, Yuexin, Forquer, Isaac P., Kelly, Jane X., Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Vaidya, Akhil B., Riscoe, Michael K.
Τόπος έκδοσης Antimicrob Agents Chemother (2016)

Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway

ανά Gall, Bryan, Pryke, Kara, Abraham, Jinu, Mizuno, Nobuyo, Botto, Sara, Sali, Tina M., Broeckel, Rebecca, Haese, Nicole, Nilsen, Aaron, Placzek, Andrew, Morrison, Thomas, Heise, Mark, Streblow, Daniel, DeFilippis, Victor
Τόπος έκδοσης J Virol (2018)

Subtle Changes in Endochin-Like Quinolone Structure Alter the Site of Inhibition within the Cytochrome bc(1) Complex of Plasmodium falciparum

ανά Stickles, Allison M., de Almeida, Mariana Justino, Morrisey, Joanne M., Sheridan, Kayla A., Forquer, Isaac P., Nilsen, Aaron, Winter, Rolf W., Burrows, Jeremy N., Fidock, David A., Vaidya, Akhil B., Riscoe, Michael K.
Τόπος έκδοσης Antimicrob Agents Chemother (2015)

MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

ανά Harriff, Melanie J., McMurtrey, Curtis, Froyd, Cara A., Jin, Haihong, Cansler, Meghan, Null, Megan, Worley, Aneta, Meermeier, Erin W., Swarbrick, Gwendolyn, Nilsen, Aaron, Lewinsohn, Deborah A., Hildebrand, William, Adams, Erin J., Lewinsohn, David M.
Τόπος έκδοσης Sci Immunol (2018)

Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses

ανά Sali, Tina M., Pryke, Kara M., Abraham, Jinu, Liu, Andrew, Archer, Iris, Broeckel, Rebecca, Staverosky, Julia A., Smith, Jessica L., Al-Shammari, Ahmed, Amsler, Lisi, Sheridan, Kayla, Nilsen, Aaron, Streblow, Daniel N., DeFilippis, Victor R.
Τόπος έκδοσης PLoS Pathog (2015)

Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner

ανά Abraham, Jinu, Botto, Sara, Mizuno, Nobuyo, Pryke, Kara, Gall, Bryan, Boehm, Dylan, Sali, Tina M., Jin, Haihong, Nilsen, Aaron, Gough, Michael, Baird, Jason, Chakhtoura, Marita, Subra, Caroline, Trautmann, Lydie, Haddad, Elias K., DeFilippis, Victor R.
Τόπος έκδοσης Front Immunol (2020)