New synthetic routes to thyroid hormone analogs: d(6)-sobetirome, (3)H-sobetirome, and the antagonist NH-3

Por Placzek, Andrew T., Scanlan, Thomas S.
Publicado no Tetrahedron (2015)

New Synthetic Methodology for the Construction of 7-Substituted Farnesyl Diphosphate Analogs

Por Placzek, Andrew T., Gibbs, Richard A.
Publicado em 2011

Synthesis of Frame-Shifted Farnesyl Diphosphate Analogs

Por Placzek, Andrew T., Hougland, James L., Gibbs, Richard A.
Publicado no Org Lett (2012)

Increasing Thyromimetic Potency Through Halogen Substitution

Por Devereaux, Jordan, Ferrara, Skylar J., Banerji, Tania, Placzek, Andrew, Scanlan, Thomas S.
Publicado no ChemMedChem (2016)

Sobetirome Prodrug Esters with Enhanced Blood-Brain Barrier Permeability

Por Placzek, Andrew T., Ferrara, Skylar J., Hartley, Meredith D., Sanford-Crane, Hannah S., Meinig, James M., Scanlan, Thomas S.
Publicado no Bioorg Med Chem (2016)

Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide)

Por Placzek, Ekaterina A., Cooper, Bruce R., Placzek, Andrew T., Chester, Julia A., Davisson, V. Jo, Barker, Eric L.
Publicado em 2010

Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration

Por Ma, Hongwei, Yang, Fan, Butler, Michael R., Belcher, Joshua, Redmond, T. Michael, Placzek, Andrew T., Scanlan, Thomas S., Ding, Xi-Qin
Publicado no FASEB J (2017)

Detection of non-sterol isoprenoids by HPLC-MS/MS

Por Henneman, Linda, van Cruchten, Arno G., Denis, Simone W., Amolins, Michael W., Placzek, Andrew T., Gibbs, Richard A., Kulik, Willem, Waterham, Hans R.
Publicado em 2008

Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy

Por Fernando, Roshini, Placzek, Ekaterina, Reese, Edmund A., Placzek, Andrew T., Schwartz, Samantha, Trierweiler, Aaron, Niziol, Leslie M., Raychaudhuri, Nupur, Atkins, Stephen, Scanlan, Thomas S., Smith, Terry J.
Publicado no J Clin Endocrinol Metab (2016)

Ester-to-Amide Rearrangement of Ethanolamine-Derived Prodrugs of Sobetirome with Increased Blood-Brain Barrier Penetration

Por Ferrara, Skylar J., Meinig, J. Matthew, Placzek, Andrew T., Banerji, Tapasree, McTigue, Peter, Hartley, Meredith D., Sanford-Crane, Hannah S., Banerji, Tania, Bourdette, Dennis, Scanlan, Thomas S.
Publicado no Bioorg Med Chem (2017)

Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway

Por Gall, Bryan, Pryke, Kara, Abraham, Jinu, Mizuno, Nobuyo, Botto, Sara, Sali, Tina M., Broeckel, Rebecca, Haese, Nicole, Nilsen, Aaron, Placzek, Andrew, Morrison, Thomas, Heise, Mark, Streblow, Daniel, DeFilippis, Victor
Publicado no J Virol (2018)

4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

Por Jeong, Suh Young, Hogarth, Penelope, Placzek, Andrew, Gregory, Allison M, Fox, Rachel, Zhen, Dolly, Hamada, Jeffrey, van der Zwaag, Marianne, Lambrechts, Roald, Jin, Haihong, Nilsen, Aaron, Cobb, Jared, Pham, Thao, Gray, Nora, Ralle, Martina, Duffy, Megan, Schwanemann, Leila, Rai, Puneet, Freed, Alison, Wakeman, Katrina, Woltjer, Randall L, Sibon, Ody CM, Hayflick, Susan J
Publicado no EMBO Mol Med (2019)