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Sobetirome Prodrug Esters with Enhanced Blood-Brain Barrier Permeability

There is currently great interest in developing drugs that stimulate myelin repair for use in demyelinating diseases such as multiple sclerosis. Thyroid hormone plays a key role in stimulating myelination during development and also controls the expression of important genes involved in myelin repai...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem
Main Authors: Placzek, Andrew T., Ferrara, Skylar J., Hartley, Meredith D., Sanford-Crane, Hannah S., Meinig, James M., Scanlan, Thomas S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297602/
https://ncbi.nlm.nih.gov/pubmed/27707627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.09.038
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