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Sobetirome Prodrug Esters with Enhanced Blood-Brain Barrier Permeability
There is currently great interest in developing drugs that stimulate myelin repair for use in demyelinating diseases such as multiple sclerosis. Thyroid hormone plays a key role in stimulating myelination during development and also controls the expression of important genes involved in myelin repai...
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| Pubblicato in: | Bioorg Med Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5297602/ https://ncbi.nlm.nih.gov/pubmed/27707627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.09.038 |
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