Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway

The type I interferon (IFN) system represents an essential innate immune response that renders cells resistant to virus growth via the molecular actions of IFN-induced effector proteins. IFN-mediated cellular states inhibit growth of numerous and diverse virus types, including those of known pathoge...

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Veröffentlicht in:J Virol
Hauptverfasser: Gall, Bryan, Pryke, Kara, Abraham, Jinu, Mizuno, Nobuyo, Botto, Sara, Sali, Tina M., Broeckel, Rebecca, Haese, Nicole, Nilsen, Aaron, Placzek, Andrew, Morrison, Thomas, Heise, Mark, Streblow, Daniel, DeFilippis, Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827377/
https://ncbi.nlm.nih.gov/pubmed/29263267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01913-17
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