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Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses

Mayaro virus (MAYV) is an alphavirus endemic to South and Central America associated with sporadic outbreaks in humans. MAYV infection causes severe joint and muscle pain that can persist for weeks to months. Currently, there are no approved vaccines or therapeutics to prevent MAYV infection or trea...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Powers, John M., Haese, Nicole N., Denton, Michael, Ando, Takeshi, Kreklywich, Craig, Bonin, Kiley, Streblow, Cassilyn E., Kreklywich, Nicholas, Smith, Patricia, Broeckel, Rebecca, DeFilippis, Victor, Morrison, Thomas E., Heise, Mark T., Streblow, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051823/
https://ncbi.nlm.nih.gov/pubmed/33793555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009308
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