MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

MR1-restricted T cells (MR1Ts) are a T cell subset that recognize and mediate host defense to a broad array of microbial pathogens, including respiratory pathogens (e.g., Mycobacterium tuberculosis, Streptococcus pyogenes, and Francisella tularensis) and enteric pathogens (e.g., Escherichia coli and...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Harriff, Melanie J., McMurtrey, Curtis, Froyd, Cara A., Jin, Haihong, Cansler, Meghan, Null, Megan, Worley, Aneta, Meermeier, Erin W., Swarbrick, Gwendolyn, Nilsen, Aaron, Lewinsohn, Deborah A., Hildebrand, William, Adams, Erin J., Lewinsohn, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085347/
https://ncbi.nlm.nih.gov/pubmed/30006464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao2556
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