MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

MR1-restricted T cells (MR1Ts) are a T cell subset that recognize and mediate host defense to a broad array of microbial pathogens, including respiratory pathogens (e.g., Mycobacterium tuberculosis, Streptococcus pyogenes, and Francisella tularensis) and enteric pathogens (e.g., Escherichia coli and...

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Pubblicato in:Sci Immunol
Autori principali: Harriff, Melanie J., McMurtrey, Curtis, Froyd, Cara A., Jin, Haihong, Cansler, Meghan, Null, Megan, Worley, Aneta, Meermeier, Erin W., Swarbrick, Gwendolyn, Nilsen, Aaron, Lewinsohn, Deborah A., Hildebrand, William, Adams, Erin J., Lewinsohn, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085347/
https://ncbi.nlm.nih.gov/pubmed/30006464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao2556
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