Alternative splicing of MR1 regulates antigen presentation to MAIT cells

Mucosal Associated Invariant T (MAIT) cells can sense intracellular infection by a broad array of pathogens. These cells are activated upon encountering microbial antigen(s) displayed by MR1 on the surface of an infected cell. Human MR1 undergoes alternative splicing. The full-length isoform, MR1A,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Narayanan, Gitanjali A., Nellore, Abhinav, Tran, Jessica, Worley, Aneta H., Meermeier, Erin W., Karamooz, Elham, Huber, Megan E., Kurapova, Regina, Tafesse, Fikadu G., Harriff, Melanie J., Lewinsohn, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508857/
https://ncbi.nlm.nih.gov/pubmed/32963314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72394-9
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