Diphenylether-modified 1,2-diamines with improved drug properties for development against Mycobacterium tuberculosis

New treatments for tuberculosis infection are critical to combat the emergence of multi-drug and extensively-drug resistant Mycobacterium tuberculosis (Mtb). We report the characterization of a diphenylether modified adamantyl 1,2-diamine that we refer to as TBL-140, which has a minimal inhibitory c...

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Bibliografske podrobnosti
izdano v:ACS Infect Dis
Main Authors: Foss, Marie H., Pou, Sovitj, Davidson, Patrick M., Dunaj, Jennifer L., Winter, Rolf W., Pou, Sovijja, Licon, Meredith H., Doh, Julia K., Li, Yuexin, Kelly, Jane X., Dodean, Rozalia A., Koop, Dennis R., Riscoe, Michael K., Purdy, Georgiana E.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742494/
https://ncbi.nlm.nih.gov/pubmed/27626102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00052
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