Pharmacokinetic study of lipoic acid in multiple sclerosis: Comparing mice and human pharmacokinetic parameters

BACKGROUND: Lipoic Acid (LA) is a natural anti-oxidant available as an oral supplement that different manufacturers produce. LA administered subcutaneously (SC) is an effective therapy for murine experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis (MS). OBJECTIVE: To compa...

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Hoofdauteurs: Yadav, Vijayshree, Marracci, Gail H., Munar, Myrna Y., Cherala, Ganesh, Stuber, Lauren E., Alvarez, Lilia, Shinto, Lynne, Koop, Dennis R., Bourdette, Dennis N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489916/
https://ncbi.nlm.nih.gov/pubmed/20150394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458509359722
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