Intestinal metabolites are profoundly altered in the context of HLA-B27 expression and functionally modulate disease in a rat model of spondyloarthropathy

OBJECTIVE: HLA-B27 associated spondyloarthropathies are associated with an altered intestinal microbiota and bowel inflammation. Therefore, we sought to identify B27-dependent changes in both host and microbial metabolites in the HLA-B27/β2m rat and whether microbiota-derived metabolites could impac...

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Detaylı Bibliyografya
Yayımlandı:Arthritis Rheumatol
Asıl Yazarlar: Asquith, Mark, Davin, Sean, Stauffer, Patrick, Michell, Claire, Janowitz, Cathleen, Lin, Phoebe, Ensign-Lewis, Joe, Kinchen, Jason M., Koop, Dennis R, Rosenbaum, James T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623151/
https://ncbi.nlm.nih.gov/pubmed/28622455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40183
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