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Inhibition of Cytochrome bc(1) as a Strategy for Single-Dose, Multi-Stage Antimalarial Therapy

Single-dose therapies for malaria have been proposed as a way to reduce the cost and increase the effectiveness of antimalarial treatment. However, no compound to date has shown single-dose activity against both the blood-stage Plasmodium parasites that cause disease and the liver-stage parasites th...

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Podrobná bibliografie
Vydáno v:Am J Trop Med Hyg
Hlavní autoři: Stickles, Allison M., Ting, Li-Min, Morrisey, Joanne M., Li, Yuexin, Mather, Michael W., Meermeier, Erin, Pershing, April M., Forquer, Isaac P., Miley, Galen P., Pou, Sovitj, Winter, Rolf W., Hinrichs, David J., Kelly, Jane X., Kim, Kami, Vaidya, Akhil B., Riscoe, Michael K., Nilsen, Aaron
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Tropical Medicine and Hygiene 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458825/
https://ncbi.nlm.nih.gov/pubmed/25918204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.14-0553
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