Bioequivalence of Two Intravenous Artesunate Products with Its Active Metabolite Following Single and Multiple Injections

by Li, Qigui, Xie, Lisa, Melendez, Victor, Weina, Peter
Published 2011

Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats

by Xie, Lisa H, Li, Qigui, Zhang, Jing, Weina, Peter J
Published 2009

Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in preclinical models of malaria

by Ohrt, Colin, Li, Qigui, Obaldia, Nicanor, Im-erbsin, Rawiwan, Xie, Lisa, Berman, Jonathan
Published 2014

New Potential Antimalarial Agents: Therapeutic-Index Evaluation of Pyrroloquinazolinediamine and Its Prodrugs in a Rat Model of Severe Malaria

by Xie, Lisa H., Li, Qigui, Lin, Ai J., Smith, Kirsten, Zhang, Jing, Skillman, Donald S.
Published 2006

Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

by Wang, Hongxing, Li, Qigui, Reyes, Sean, Zhang, Jing, Xie, Lisa, Melendez, Victor, Hickman, Mark, Kozar, Michael P.
Published 2013

Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections

by Li, Qigui, O’Neil, Michael, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Pybus, Brandon, Hickman, Mark, Melendez, Victor
Published 2014

Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model

by Fracisco, Susan, Teja-isavadharm, Paktiya, Gettayacamin, Montip, Berman, Jonathan, Li, Qigui, Melendez, Victor, Saunders, David, Xie, Lisa, Ohrt, Colin
Published 2014

Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

by Li, Qigui, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Roncal, Norma, Zhang, Ping, Vuong, Chau, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Read, Lisa, Hickman, Mark
Published in Malar Res Treat (2017)

Pharmacokinetics, Safety, and Hydrolysis of Oral Pyrroloquinazolinediamines Administered in Single and Multiple Doses in Rats

by Li, Qigui, Kozar, Michael P., Shearer, Todd W., Xie, Lisa H., Lin, Ai J., Smith, Kirsten S., Si, Yuanzheng, Anova, Lalaine, Zhang, Jing, Milhous, Wilbur K., Skillman, Donald R.
Published 2007

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

by Milner, Erin E., Berman, Jonathan, Caridha, Diana, Dickson, Samuel P., Hickman, Mark, Lee, Patricia J., Marcsisin, Sean R., Read, Lisa T., Roncal, Norma, Vesely, Brian A., Xie, Lisa H., Zhang, Jing, Zhang, Ping, Li, Qigui
Published in Malar J (2016)

Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants

by Jin, Xiannu, Potter, Brittney, Luong, Thu-lan, Nelson, Jennifer, Vuong, Chau, Potter, Corttney, Xie, Lisa, Zhang, Jing, Zhang, Ping, Sousa, Jason, Li, Qigui, Pybus, Brandon S., Kreishman-Deitrick, Mara, Hickman, Mark, Smith, Philip L., Paris, Robert, Reichard, Gregory, Marcsisin, Sean R.
Published in Malar J (2016)

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

by Caridha, Diana, Hickman, Mark, Xie, Lisa, Ngundam, Franklyn, Milner, Erin, Schenk, Amanda, Butler, Kirk, Nugent, Dylan, Lee, Patricia, Roncal, Norma, Leed, Susan, Hosford, Eve, Lee, Jangwoo, Sciotti, Richard J., Reichard, Gregory, Black, Chad, Kreishman-Deitrick, Mara, Li, Qigui, Vesely, Brian
Published in Malar J (2019)

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria

by Frueh, Lisa, LI, Yuexin, Mather, Michael W., Li, Qigui, Pou, Sovitj, Nilsen, Aaron, Winter, Rolf W., Forquer, Isaac P., Pershing, April M., Xie, Lisa H., Smilkstein, Martin J., Caridha, Diana, Campbell, Robert F., Sciotti, Richard J., Kreishman-Deitrick, Mara, Kelly, Jane X., Vesely, Brian, Vaidya, Akhil B., Riscoe, Michael K
Published in ACS Infect Dis (2017)

Differential Cytochrome P450 2D Metabolism Alters Tafenoquine Pharmacokinetics

by Vuong, Chau, Xie, Lisa H., Potter, Brittney M. J., Zhang, Jing, Zhang, Ping, Duan, Dehui, Nolan, Christina K., Sciotti, Richard J., Zottig, Victor E., Nanayakkara, N. P. Dhammika, Tekwani, Babu L., Walker, Larry A., Smith, Philip L., Paris, Robert M., Read, Lisa T., Li, Qigui, Pybus, Brandon S., Sousa, Jason C., Reichard, Gregory A., Smith, Bryan, Marcsisin, Sean R.
Published in Antimicrob Agents Chemother (2015)

Differential CYP 2D6 Metabolism Alters Primaquine Pharmacokinetics

by Potter, Brittney M. J., Xie, Lisa H., Vuong, Chau, Zhang, Jing, Zhang, Ping, Duan, Dehui, Luong, Thu-Lan T., Bandara Herath, H. M. T., Dhammika Nanayakkara, N. P., Tekwani, Babu L., Walker, Larry A., Nolan, Christina K., Sciotti, Richard J., Zottig, Victor E., Smith, Philip L., Paris, Robert M., Read, Lisa T., Li, Qigui, Pybus, Brandon S., Sousa, Jason C., Reichard, Gregory A., Marcsisin, Sean R.
Published in Antimicrob Agents Chemother (2015)

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials

by Dodean, Rozalia A., Kancharla, Papireddy, Li, Yuexin, Melendez, Victor, Read, Lisa, Bane, Charles E., Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J., Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E., Nolan, Christina, Huezo, Stephanie J., Rasmussen, Stephanie A., Stephens, Melissa T., Tan, John C., Cooper, Roland A., Smilkstein, Martin J., Pou, Sovitj, Winter, Rolf W., Riscoe, Michael K., Kelly, Jane X.
Published in J Med Chem (2019)

Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials

by Kancharla, Papireddy, Dodean, Rozalia A., Li, Yuexin, Pou, Sovitj, Pybus, Brandon, Melendez, Victor, Read, Lisa, Bane, Charles E., Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J., Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E., Nolan, Christina, Ceja, Frida G., Rasmussen, Stephanie A., Tumwebaze, Patrick K., Rosenthal, Philip J., Mu, Jianbing, Bayles, Brett R., Cooper, Roland A., Reynolds, Kevin A., Smilkstein, Martin J., Riscoe, Michael K., Kelly, Jane X.
Published in J Med Chem (2020)