Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants

BACKGROUND: The liver-stage anti-malarial activity of primaquine and other 8-aminoquinoline molecules has been linked to bio-activation through CYP 2D6 metabolism. Factors such as CYP 2D6 poor metabolizer status and/or co-administration of drugs that inhibit/interact with CYP 2D6 could alter the pha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Jin, Xiannu, Potter, Brittney, Luong, Thu-lan, Nelson, Jennifer, Vuong, Chau, Potter, Corttney, Xie, Lisa, Zhang, Jing, Zhang, Ping, Sousa, Jason, Li, Qigui, Pybus, Brandon S., Kreishman-Deitrick, Mara, Hickman, Mark, Smith, Philip L., Paris, Robert, Reichard, Gregory, Marcsisin, Sean R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869338/
https://ncbi.nlm.nih.gov/pubmed/27188854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1329-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados