Assessment and Continued Validation of the Malaria SYBR Green I-Based Fluorescence Assay for Use in Malaria Drug Screening

Por Johnson, Jacob D., Dennull, Richard A., Gerena, Lucia, Lopez-Sanchez, Miriam, Roncal, Norma E., Waters, Norman C.
Publicado em 2007

Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine

Por Wipf, Peter, Mo, Tingting, Geib, Steven J., Caridha, Diana, Dow, Geoffrey S., Gerena, Lucia, Roncal, Norma, Milner, Erin E.
Publicado em 2009

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery

Por Patel, Gautam, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Erath, Jessey, Rodriguez, Ana, Sciotti, Richard J., Pollastri, Michael P.
Publicado em 2014

Kinase scaffold repurposing for neglected disease drug discovery: Discovery of an efficacious, lapatanib-derived lead compound for trypanosomiasis

Por Patel, Gautam, Karver, Caitlin E., Behera, Ranjan, Guyett, Paul, Sullenberger, Catherine, Edwards, Peter, Roncal, Norma E., Mensa-Wilmot, Kojo, Pollastri, Michael P.
Publicado em 2013

Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box against Intracellular Leishmania major Amastigotes

Por Khraiwesh, Mozna, Leed, Susan, Roncal, Norma, Johnson, Jacob, Sciotti, Richard, Smith, Philip, Read, Lisa, Paris, Robert, Hudson, Thomas, Hickman, Mark, Grogl, Max
Publicado no Am J Trop Med Hyg (2016)

Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community

Por Branch, OraLee, Casapia, W Martin, Gamboa, Dionicia V, Hernandez, Jean N, Alava, Freddy F, Roncal, Norma, Alvarez, Eugenia, Perez, Enrique J, Gotuzzo, Eduardo
Publicado em 2005

Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

Por Li, Qigui, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Roncal, Norma, Zhang, Ping, Vuong, Chau, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Read, Lisa, Hickman, Mark
Publicado no Malar Res Treat (2017)

Effects of Point Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropterate Synthase Genes on Clinical Outcomes and In Vitro Susceptibility to Sulfadoxine and Py...

Por Bacon, David J., Tang, Doug, Salas, Carola, Roncal, Norma, Lucas, Carmen, Gerena, Lucia, Tapia, Lorena, Llanos-Cuentas, A. Alejandro, Garcia, Coralith, Solari, Lelv, Kyle, Dennis, Magill, Alan J.
Publicado em 2009

Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

Por Milner, Erin, McCalmont, William, Bhonsle, Jayendra, Caridha, Diana, Cobar, Jose, Gardner, Sean, Gerena, Lucia, Goodine, Duane, Lanteri, Charlotte, Melendez, Victor, Roncal, Norma, Sousa, Jason, Wipf, Peter, Dow, Geoffrey Stuart
Publicado em 2010

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery

Por Devine, William, Woodring, Jennifer L., Swaminathan, Uma, Amata, Emanuele, Patel, Gautam, Erath, Jessey, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Pollastri, Michael P.
Publicado no J Med Chem (2015)

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

Por Milner, Erin E., Berman, Jonathan, Caridha, Diana, Dickson, Samuel P., Hickman, Mark, Lee, Patricia J., Marcsisin, Sean R., Read, Lisa T., Roncal, Norma, Vesely, Brian A., Xie, Lisa H., Zhang, Jing, Zhang, Ping, Li, Qigui
Publicado no Malar J (2016)

Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

Por Amata, Emanuele, Xi, Hualin, Colmenarejo, Gonzalo, Gonzalez-Diaz, Rosario, Cordon-Obras, Carlos, Berlanga, Manuela, Manzano, Pilar, Erath, Jessey, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Sciotti, Richard J., Navarro, Miguel, Pollastri, Michael P.
Publicado no ACS Infect Dis (2016)

Targeting the Fatty Acid Biosynthesis Enzyme, β-Ketoacyl–Acyl Carrier Protein Synthase III (PfKASIII), in the Identification of Novel Antimalarial Agents

Por Lee, Patricia J., Bhonsle, Jayendra B., Gaona, Heather W., Huddler, Donald P., Heady, Tiffany N., Kreishman-Deitrick, Mara, Bhattacharjee, Apurba, McCalmont, William F., Gerena, Lucia, Lopez-Sanchez, Miriam, Roncal, Norma E., Hudson, Thomas H., Johnson, Jacob D., Prigge, Sean T., Waters, Norman C.
Publicado em 2009

Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

Por Dow, Geoffrey S, Milner, Erin, Bathurst, Ian, Bhonsle, Jayendra, Caridha, Diana, Gardner, Sean, Gerena, Lucia, Kozar, Michael, Lanteri, Charlotte, Mannila, Anne, McCalmont, William, Moon, Jay, Read, Kevin D, Norval, Suzanne, Roncal, Norma, Shackleford, David M, Sousa, Jason, Steuten, Jessica, White, Karen L, Zeng, Qiang, Charman, Susan A
Publicado em 2011

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

Por Marcsisin, Sean R, Sousa, Jason C, Reichard, Gregory A, Caridha, Diana, Zeng, Qiang, Roncal, Norma, McNulty, Ronan, Careagabarja, Julio, Sciotti, Richard J, Bennett, Jason W, Zottig, Victor E, Deye, Gregory, Li, Qigui, Read, Lisa, Hickman, Mark, Nanayakkara, N P Dhammika, Walker, Larry A, Smith, Bryan, Melendez, Victor, Pybus, Brandon S
Publicado em 2014