Načítá se...

Kinase scaffold repurposing for neglected disease drug discovery: Discovery of an efficacious, lapatanib-derived lead compound for trypanosomiasis

Human African trypanosomiasis (HAT) is a neglected tropical disease caused by the protozoan parasite Trypanosoma brucei. Since drugs in use against HAT are toxic and require intravenous dosing, new drugs are needed. Initiating lead discovery campaigns by using chemical scaffolds from drugs approved...

Celý popis

Uloženo v:

Podrobná bibliografie
Hlavní autoři:	Patel, Gautam, Karver, Caitlin E., Behera, Ranjan, Guyett, Paul, Sullenberger, Catherine, Edwards, Peter, Roncal, Norma E., Mensa-Wilmot, Kojo, Pollastri, Michael P.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2013
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3663906/ https://ncbi.nlm.nih.gov/pubmed/23597080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400349k
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo otaguje tento záznam!

Kinase scaffold repurposing for neglected disease drug discovery: Discovery of an efficacious, lapatanib-derived lead compound for trypanosomiasis

Podobné jednotky