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New Chemical Scaffolds for Human African Trypanosomiasis Lead Discovery from a Screen of Tyrosine Kinase Inhibitor Drugs

Human African trypanosomiasis (HAT) is caused by the protozoan Trypanosoma brucei. New drugs are needed to treat HAT because of undesirable side effects and difficulties in the administration of the antiquated drugs that are currently used. In human proliferative diseases, protein tyrosine kinase (P...

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Detalhes bibliográficos
Main Authors: Behera, Ranjan, Thomas, Sarah M., Mensa-Wilmot, Kojo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023774/
https://ncbi.nlm.nih.gov/pubmed/24468788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01691-13
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