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New Chemical Scaffolds for Human African Trypanosomiasis Lead Discovery from a Screen of Tyrosine Kinase Inhibitor Drugs

Human African trypanosomiasis (HAT) is caused by the protozoan Trypanosoma brucei. New drugs are needed to treat HAT because of undesirable side effects and difficulties in the administration of the antiquated drugs that are currently used. In human proliferative diseases, protein tyrosine kinase (P...

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Hlavní autoři: Behera, Ranjan, Thomas, Sarah M., Mensa-Wilmot, Kojo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023774/
https://ncbi.nlm.nih.gov/pubmed/24468788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01691-13
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