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New Chemical Scaffolds for Human African Trypanosomiasis Lead Discovery from a Screen of Tyrosine Kinase Inhibitor Drugs

Human African trypanosomiasis (HAT) is caused by the protozoan Trypanosoma brucei. New drugs are needed to treat HAT because of undesirable side effects and difficulties in the administration of the antiquated drugs that are currently used. In human proliferative diseases, protein tyrosine kinase (P...

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Autors principals: Behera, Ranjan, Thomas, Sarah M., Mensa-Wilmot, Kojo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023774/
https://ncbi.nlm.nih.gov/pubmed/24468788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01691-13
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