Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery

[Image: see text] Tropical protozoal infections are a significant cause of morbidity and mortality worldwide; four in particular (human African trypanosomiasis (HAT), Chagas disease, cutaneous leishmaniasis, and malaria) have an estimated combined burden of over 87 million disability-adjusted life y...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Devine, William, Woodring, Jennifer L., Swaminathan, Uma, Amata, Emanuele, Patel, Gautam, Erath, Jessey, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Pollastri, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515785/
https://ncbi.nlm.nih.gov/pubmed/26087257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00515
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