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Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation
[Image: see text] Discovery of new chemotherapeutic lead agents can be accelerated by optimizing chemotypes proven to be effective in other diseases to act against parasites. One such medicinal chemistry campaign has focused on optimizing the anilinoquinazoline drug lapatinib (1) and the alkynyl thi...
Gardado en:
| Publicado en: | ACS Med Chem Lett |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2018
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187419/ https://ncbi.nlm.nih.gov/pubmed/30344906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00245 |
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