Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites

[Image: see text] Human African trypanosomiasis (HAT), Chagas disease, and leishmaniasis present a significant burden across the developing world. Existing therapeutics for these protozoal neglected tropical diseases suffer from severe side effects and toxicity. Previously, NEU-1045 (3) was identifi...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Devine, William, Thomas, Sarah M., Erath, Jessey, Bachovchin, Kelly A., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Sciotti, Richard J., Mensa-Wilmot, Kojo, Pollastri, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346991/
https://ncbi.nlm.nih.gov/pubmed/28337329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00011
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