The IGF Pathway Regulates ERα through a S6K1-Dependent Mechanism in Breast Cancer Cells

Por Becker, Marc A., Ibrahim, Yasir H., Cui, Xiaojiang, Lee, Adrian V., Yee, Douglas
Publicado em 2011

Progesterone Receptor-B Regulation of Insulin-Like Growth Factor–Stimulated Cell Migration in Breast Cancer Cells via Insulin Receptor Substrate-2

Por Ibrahim, Yasir H., Byron, Sara A., Cui, Xiaojiang, Lee, Adrian V., Yee, Douglas
Publicado em 2008

Comparison of Once-Daily versus Twice-Daily Administration of Cefdinir against Typical Bacterial Respiratory Tract Pathogens

Por Ross, Gigi H., Hovde, Laurie Baeker, Ibrahim, Khalid H., Ibrahim, Yasir H., Rotschafer, John C.
Publicado em 2001

Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer

Por Becker, Marc A., Ibrahim, Yasir H., Oh, Annabell S., Fagan, Dedra H., Byron, Sara A., Sarver, Aaron L., Lee, Adrian V., Shaw, Leslie M., Fan, Cheng, Perou, Charles M., Yee, Douglas
Publicado no PLoS One (2016)

The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue

Por Wada, Shogo, Neinast, Michael, Jang, Cholsoon, Ibrahim, Yasir H., Lee, Gina, Babu, Apoorva, Li, Jian, Hoshino, Atsushi, Rowe, Glenn C., Rhee, James, Martina, José A., Puertollano, Rosa, Blenis, John, Morley, Michael, Baur, Joseph A., Seale, Patrick, Arany, Zoltan
Publicado no Genes Dev (2016)

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2(+) breast cancer patients

Por Scaltriti, Maurizio, Eichhorn, Pieter J., Cortés, Javier, Prudkin, Ludmila, Aura, Claudia, Jiménez, José, Chandarlapaty, Sarat, Serra, Violeta, Prat, Aleix, Ibrahim, Yasir H., Guzmán, Marta, Gili, Magui, Rodríguez, Olga, Rodríguez, Sonia, Pérez, José, Green, Simon R., Mai, Sabine, Rosen, Neal, Hudis, Clifford, Baselga, José
Publicado em 2011

RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer

Por Serra, Violeta, Eichhorn, Pieter J.A., García-García, Celina, Ibrahim, Yasir H., Prudkin, Ludmila, Sánchez, Gertrudis, Rodríguez, Olga, Antón, Pilar, Parra, Josep-Lluís, Marlow, Sara, Scaltriti, Maurizio, Pérez-Garcia, José, Prat, Aleix, Arribas, Joaquín, Hahn, William C., Kim, So Young, Baselga, José
Publicado em 2013

Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer

Por Juvekar, Ashish, Burga, Laura N., Hu, Hai, Lunsford, Elaine P., Ibrahim, Yasir H., Balmañà, Judith, Rajendran, Anbazhagan, Papa, Antonella, Spencer, Katherine, Lyssiotis, Costas A., Nardella, Caterina, Pandolfi, Pier Paolo, Baselga, Jose, Scully, Ralph, Asara, John M., Cantley, Lewis C., Wulf, Gerburg M.
Publicado em 2012

RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer

Por Serra, Violeta, Eichhorn, Pieter J.A., García-García, Celina, Ibrahim, Yasir H., Prudkin, Ludmila, Sánchez, Gertrudis, Rodríguez, Olga, Antón, Pilar, Parra, Josep-Lluís, Marlow, Sara, Scaltriti, Maurizio, Pérez-Garcia, José, Prat, Aleix, Arribas, Joaquín, Hahn, William C., Kim, So Young, Baselga, José
Publicado em 2014

Targeting a cell state common to triple-negative breast cancers

Por Muellner, Markus K, Mair, Barbara, Ibrahim, Yasir, Kerzendorfer, Claudia, Lechtermann, Hannelore, Trefzer, Claudia, Klepsch, Freya, Müller, André C, Leitner, Ernestine, Macho-Maschler, Sabine, Superti-Furga, Giulio, Bennett, Keiryn L, Baselga, José, Rix, Uwe, Kubicek, Stefan, Colinge, Jacques, Serra, Violeta, Nijman, Sebastian MB
Publicado no Mol Syst Biol (2015)

PI3K Inhibition Impairs BRCA1/2 Expression and Sensitizes BRCA-Proficient Triple-Negative Breast Cancer to PARP Inhibition

Por Ibrahim, Yasir H., García-García, Celina, Serra, Violeta, He, Lei, Torres-Lockhart, Kristine, Prat, Aleix, Anton, Pilar, Cozar, Patricia, Guzmán, Marta, Grueso, Judit, Rodríguez, Olga, Calvo, Maria Teresa, Aura, Claudia, Díez, Orland, Rubio, Isabel T., Pérez, José, Rodón, Jordi, Cortés, Javier, Ellisen, Leif W., Scaltriti, Maurizio, Baselga, José
Publicado no Cancer Discov (2012)

mTORC1 Inhibition Is Required for Sensitivity to PI3K p110α Inhibitors in PIK3CA-Mutant Breast Cancer

Por Elkabets, Moshe, Vora, Sadhna, Juric, Dejan, Morse, Natasha, Mino-Kenudson, Mari, Muranen, Taru, Tao, Jessica, Campos, Ana Bosch, Rodon, Jordi, Ibrahim, Yasir H., Serra, Violeta, Rodrik-Outmezguine, Vanessa, Hazra, Saswati, Singh, Sharat, Kim, Phillip, Quadt, Cornelia, Liu, Manway, Huang, Alan, Rosen, Neal, Engelman, Jeffrey A., Scaltriti, Maurizio, Baselga, José
Publicado em 2013

MEK plus PI3K/mTORC1/2 therapeutic efficacy is impacted by TP53 mutation in preclinical models of colorectal cancer

Por García-García, Celina, Rivas, Martín A., Ibrahim, Yasir H., Calvo, María Teresa, Gris-Oliver, Albert, Rodríguez, Olga, Grueso, Judit, Antón, Pilar, Guzmán, Marta, Aura, Claudia, Nuciforo, Paolo, Jessen, Katti, Argilés, Guillem, Dienstmann, Rodrigo, Bertotti, Andrea, Trusolino, Livio, Matito, Judit, Vivancos, Ana, Chicote, Irene, Palmer, Héctor G., Tabernero, Josep, Scaltriti, Maurizio, Baselga, José, Serra, Violeta
Publicado no Clin Cancer Res (2015)

PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer

Por Bosch, Ana, Li, Zhiqiang, Bergamaschi, Anna, Ellis, Haley, Toska, Eneda, Prat, Aleix, Tao, Jessica J., Spratt, Daniel E., Viola-Villegas, Nerissa T., Castel, Pau, Minuesa, Gerard, Morse, Natasha, Rodón, Jordi, Ibrahim, Yasir, Cortes, Javier, Perez-Garcia, Jose, Galvan, Patricia, Grueso, Judit, Guzman, Marta, Katzenellenbogen, John A., Kharas, Michael, Lewis, Jason S., Dickler, Maura, Serra, Violeta, Rosen, Neal, Chandarlapaty, Sarat, Scaltriti, Maurizio, Baselga, José
Publicado no Sci Transl Med (2015)

Stratification and therapeutic potential of PML in metastatic breast cancer

Por Martín-Martín, Natalia, Piva, Marco, Urosevic, Jelena, Aldaz, Paula, Sutherland, James D., Fernández-Ruiz, Sonia, Arreal, Leire, Torrano, Verónica, Cortazar, Ana R., Planet, Evarist, Guiu, Marc, Radosevic-Robin, Nina, Garcia, Stephane, Macías, Iratxe, Salvador, Fernando, Domenici, Giacomo, Rueda, Oscar M., Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Valcárcel-Jiménez, Lorea, Sánchez-Mosquera, Pilar, Varela-Rey, Marta, Martínez-Chantar, Maria Luz, Anguita, Juan, Ibrahim, Yasir H., Scaltriti, Maurizio, Lawrie, Charles H., Aransay, Ana M., Iovanna, Juan L., Baselga, Jose, Caldas, Carlos, Barrio, Rosa, Serra, Violeta, dM Vivanco, Maria, Matheu, Ander, Gomis, Roger R., Carracedo, Arkaitz
Publicado no Nat Commun (2016)