Stratification and therapeutic potential of PML in metastatic breast cancer

Patient stratification has been instrumental for the success of targeted therapies in breast cancer. However, the molecular basis of metastatic breast cancer and its therapeutic vulnerabilities remain poorly understood. Here we show that PML is a novel target in aggressive breast cancer. The acquisi...

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Publicado no:Nat Commun
Main Authors: Martín-Martín, Natalia, Piva, Marco, Urosevic, Jelena, Aldaz, Paula, Sutherland, James D., Fernández-Ruiz, Sonia, Arreal, Leire, Torrano, Verónica, Cortazar, Ana R., Planet, Evarist, Guiu, Marc, Radosevic-Robin, Nina, Garcia, Stephane, Macías, Iratxe, Salvador, Fernando, Domenici, Giacomo, Rueda, Oscar M., Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Valcárcel-Jiménez, Lorea, Sánchez-Mosquera, Pilar, Varela-Rey, Marta, Martínez-Chantar, Maria Luz, Anguita, Juan, Ibrahim, Yasir H., Scaltriti, Maurizio, Lawrie, Charles H., Aransay, Ana M., Iovanna, Juan L., Baselga, Jose, Caldas, Carlos, Barrio, Rosa, Serra, Violeta, dM Vivanco, Maria, Matheu, Ander, Gomis, Roger R., Carracedo, Arkaitz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999521/
https://ncbi.nlm.nih.gov/pubmed/27553708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12595
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