Stratification and therapeutic potential of PML in metastatic breast cancer

Patient stratification has been instrumental for the success of targeted therapies in breast cancer. However, the molecular basis of metastatic breast cancer and its therapeutic vulnerabilities remain poorly understood. Here we show that PML is a novel target in aggressive breast cancer. The acquisi...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Martín-Martín, Natalia, Piva, Marco, Urosevic, Jelena, Aldaz, Paula, Sutherland, James D., Fernández-Ruiz, Sonia, Arreal, Leire, Torrano, Verónica, Cortazar, Ana R., Planet, Evarist, Guiu, Marc, Radosevic-Robin, Nina, Garcia, Stephane, Macías, Iratxe, Salvador, Fernando, Domenici, Giacomo, Rueda, Oscar M., Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Valcárcel-Jiménez, Lorea, Sánchez-Mosquera, Pilar, Varela-Rey, Marta, Martínez-Chantar, Maria Luz, Anguita, Juan, Ibrahim, Yasir H., Scaltriti, Maurizio, Lawrie, Charles H., Aransay, Ana M., Iovanna, Juan L., Baselga, Jose, Caldas, Carlos, Barrio, Rosa, Serra, Violeta, dM Vivanco, Maria, Matheu, Ander, Gomis, Roger R., Carracedo, Arkaitz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999521/
https://ncbi.nlm.nih.gov/pubmed/27553708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12595
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