Stratification and therapeutic potential of PML in metastatic breast cancer

Patient stratification has been instrumental for the success of targeted therapies in breast cancer. However, the molecular basis of metastatic breast cancer and its therapeutic vulnerabilities remain poorly understood. Here we show that PML is a novel target in aggressive breast cancer. The acquisi...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Martín-Martín, Natalia, Piva, Marco, Urosevic, Jelena, Aldaz, Paula, Sutherland, James D., Fernández-Ruiz, Sonia, Arreal, Leire, Torrano, Verónica, Cortazar, Ana R., Planet, Evarist, Guiu, Marc, Radosevic-Robin, Nina, Garcia, Stephane, Macías, Iratxe, Salvador, Fernando, Domenici, Giacomo, Rueda, Oscar M., Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Valcárcel-Jiménez, Lorea, Sánchez-Mosquera, Pilar, Varela-Rey, Marta, Martínez-Chantar, Maria Luz, Anguita, Juan, Ibrahim, Yasir H., Scaltriti, Maurizio, Lawrie, Charles H., Aransay, Ana M., Iovanna, Juan L., Baselga, Jose, Caldas, Carlos, Barrio, Rosa, Serra, Violeta, dM Vivanco, Maria, Matheu, Ander, Gomis, Roger R., Carracedo, Arkaitz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999521/
https://ncbi.nlm.nih.gov/pubmed/27553708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12595
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