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FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state

Forkhead box protein A1 (FOXA1) is a pioneer transcription factor that contributes to chromatin opening to allow binding of estrogen receptor (ER) in ER+ breast cancer. Mutations in FOXA1 are recurrent in breast cancer but the functional consequences of these mutations remain unknown. We identified...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Arruabarrena-Aristorena, Amaia, Toska, Eneda
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128199/
https://ncbi.nlm.nih.gov/pubmed/34027035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1891831
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